INT122077

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Context Info
Confidence 0.32
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 1.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Crygb) cytoplasm (Crygb)
Anatomy Link Frequency
brain 2
Crygb (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 4 99.76 Very High Very High Very High
Spinal cord 1 99.68 Very High Very High Very High
addiction 7 96.28 Very High Very High Very High
tolerance 7 95.68 Very High Very High Very High
Analgesic 1 95.28 Very High Very High Very High
Opioid 7 94.40 High High
nMDA receptor 2 92.32 High High
orphanin 3 90.72 High High
opioid receptor 1 72.08 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 1 88.72 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Chronic morphine-treatments increased NOP gene or epsilon1 subunit protein expression in the spinal cord or specific brain loci, respectively.
Positive_regulation (increased) of Gene_expression (expression) of NOP in brain associated with spinal cord and morphine
1) Confidence 0.32 Published 2004 Journal Novartis Found. Symp. Section Abstract Doc Link 15469049 Disease Relevance 0.09 Pain Relevance 1.87

General Comments

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