INT122086

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Context Info
Confidence 0.45
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SGCG) cytoskeleton (SGCG) cytoskeleton organization (SGCG)
cytoplasm (SGCG)
SGCG (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 5 98.20 Very High Very High Very High
opioid receptor 5 97.48 Very High Very High Very High
Potency 1 79.56 Quite High
Antinociceptive 1 79.24 Quite High
Opioid 1 44.88 Quite Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These molecular changes include the up-regulation and augmented phosphorylation of adenylyl cyclase type II isoforms, which underlies the ability of morphine to shift opioid receptor G protein signalling from predominantly Gialpha inhibitory to Gbetagamma stimulatory.
Positive_regulation (augmented) of Phosphorylation (phosphorylation) of type associated with opioid receptor and morphine
1) Confidence 0.45 Published 2004 Journal Novartis Found. Symp. Section Abstract Doc Link 15469050 Disease Relevance 0 Pain Relevance 0.71

General Comments

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