INT122106

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Context Info
Confidence 0.69
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.95
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cdh2) plasma membrane (Cdh2) protein complex (Cdh2)
Anatomy Link Frequency
cardiac myocytes 1
synapses 1
dorsal horn 1
Cdh2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn 4 99.74 Very High Very High Very High
Spinal cord 4 93.48 High High
Neuropathic pain 2 90.88 High High
Sciatic nerve 2 89.40 High High
Hyperalgesia 2 88.80 High High
c fibre 4 87.60 High High
Abeta 2 82.12 Quite High
sodium channel 11 59.60 Quite High
Pain 2 53.36 Quite High
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 6 95.96 Very High Very High Very High
Malignant Neoplastic Disease 1 92.52 High High
Nociception 2 92.24 High High
Neuropathic Pain 2 90.88 High High
Adhesions 13 88.96 High High
Hyperalgesia 2 88.80 High High
Heart Arrhythmia 5 29.28 Quite Low
Arrhythmias 2 Under Development 1 23.20 Low Low
Sudden Death 3 20.88 Low Low
Cleidocranial Dysplasia 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Within the first 7 d after axotomy, E-cadherin is rapidly and completely lost from the dorsal horn synapses with which it is affiliated, whereas N-cadherin localization and levels are unchanged; such patterns persist through 28 d postlesion.
Localization (localization) of N-cadherin in synapses associated with dorsal horn
1) Confidence 0.69 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15470146 Disease Relevance 0.51 Pain Relevance 0.61
Here, we demonstrate in adult rat dorsal horn that E- and N-cadherin display unique patterns of localization to functionally distinct types of synapses of intrinsic and primary afferent origin.
Localization (localization) of N-cadherin in dorsal horn associated with dorsal horn
2) Confidence 0.56 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15470146 Disease Relevance 0.35 Pain Relevance 0.36
Prior work by Kostin et al. [25] demonstrated that, in primary adult rat cardiac myocytes in primary culture, both adherens junctions (as determined by immunolocalization of N-cadherin and ?
Spec (determined) Localization (immunolocalization) of N-cadherin in cardiac myocytes
3) Confidence 0.21 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2868981 Disease Relevance 0.09 Pain Relevance 0.03

General Comments

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