INT122107

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cdh2) plasma membrane (Cdh2) protein complex (Cdh2)
lysosome (Plbd2)
Anatomy Link Frequency
lamina 1
Plbd2 (Rattus norvegicus)
Cdh2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
c fibre 2 100.00 Very High Very High Very High
Dorsal horn 2 92.32 High High
Abeta 1 86.72 High High
Spinal cord 2 86.32 High High
Sciatic nerve 1 72.80 Quite High
Neuropathic pain 1 70.08 Quite High
Hyperalgesia 1 37.52 Quite Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 1 99.58 Very High Very High Very High
Injury 3 88.80 High High
Adhesions 1 81.80 Quite High
Neuropathic Pain 1 70.08 Quite High
Hyperalgesia 1 37.52 Quite Low
Pain 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Within the nociceptive afferent pathway to lamina II, nonpeptidergic C-fiber synapses in the deeper half of lamina II (IIi) contain E-cadherin but mostly lack N-cadherin, whereas the majority of the peptidergic C-fiber synapses in the outer half of lamina II (IIo) contain N-cadherin but lack E-cadherin.
lamina II Negative_regulation (lack) of N-cadherin in lamina associated with nociception and c fibre
1) Confidence 0.03 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15470146 Disease Relevance 0.42 Pain Relevance 0.50

General Comments

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