INT122116

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grin2b) embryo development (Grin2b)
Grin2b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 2 96.76 Very High Very High Very High
nMDA receptor 3 95.64 Very High Very High Very High
intrathecal 2 91.00 High High
Analgesic 1 77.56 Quite High
antagonist 1 77.00 Quite High
Spinal cord 1 71.40 Quite High
Lasting pain 1 65.04 Quite High
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 3 96.76 Very High Very High Very High
Nociception 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results indicate that the use of siRNA targeting the NR2B subunit not only decreased the expression of NR2B mRNA and its associated protein, as demonstrated by real-time PCR and Western blotting, but also abolished formalin-induced pain behaviors in rat model.
Negative_regulation (decreased) of Transcription (expression) of NR2B associated with pain
1) Confidence 0.43 Published 2005 Journal Gene Ther. Section Abstract Doc Link 15470478 Disease Relevance 0.34 Pain Relevance 0.62

General Comments

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