INT122196

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.47
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 2.07
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TAL1) enzyme binding (TAL1) DNA binding (TAL1)
TAL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 96.04 Very High Very High Very High
Pain 6 94.04 High High
visual analogue scale 5 93.52 High High
antagonist 1 78.48 Quite High
Osteoarthritis 4 75.00 Quite High
rheumatoid arthritis 35 50.00 Quite Low
corticosteroid 2 37.12 Quite Low
methotrexate 3 27.96 Quite Low
alcohol 1 25.96 Quite Low
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 2 99.12 Very High Very High Very High
Proteinuria 1 96.68 Very High Very High Very High
INFLAMMATION 7 95.84 Very High Very High Very High
Pancreatic Cancer 3 94.12 High High
Pain 4 94.04 High High
Pressure And Volume Under Development 21 92.08 High High
Adenocarcinoma 1 91.48 High High
Allergic Dermatitis 1 90.24 High High
Familial Partial Lipodystrophy 16 82.52 Quite High
Cancer 9 81.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Greater improvement in patients who received the DMW product was achieved by the second injection persistent at 16 weeks.
Gene_expression (received) of DMW product
1) Confidence 0.47 Published 2008 Journal Clin. Rheumatol. Section Abstract Doc Link 18204873 Disease Relevance 0.32 Pain Relevance 0.40
Production of the COX product, prostaglandin E2, correlated with expression of cPLA2 and COX-2 and was blocked by non-steroidal anti-inflammatory drugs (NSAIDs, indomethacin or NS398).
Gene_expression (Production) of COX product associated with inflammation and cinod
2) Confidence 0.05 Published 2004 Journal Cancer Biol. Ther. Section Abstract Doc Link 15477758 Disease Relevance 0.59 Pain Relevance 0.23
4 isoform (present in two FPLD3 subjects) was associated with quantitative loss of expression of the allele product, with no qualitative abnormalities of the encoded protein [9].
Gene_expression (expression) of allele product associated with congenital anomalies
3) Confidence 0.01 Published 2006 Journal BMC Med Genet Section Body Doc Link PMC1368963 Disease Relevance 0.10 Pain Relevance 0
Certain PPARG missense mutations in FPLD3 – such as V290M and P467L – appear to act through a dominant negative mechanism, in which the mutant allele product is expressed and then interferes with the function of the product of the wild-type allele, resulting in markedly depressed net receptor activity [6,7].
Gene_expression (expressed) of allele product
4) Confidence 0.01 Published 2006 Journal BMC Med Genet Section Body Doc Link PMC1368963 Disease Relevance 0.55 Pain Relevance 0
The following tests were either negative or normal: ESR, ANA, anti-Ro, anti-La, SCL-70, rheumatoid factor, p-ANCA, and anti-myeloperoxidase antibodies.
Gene_expression (anti-Ro) of SCL-70
5) Confidence 0.00 Published 2004 Journal Clin Mol Allergy Section Body Doc Link PMC425596 Disease Relevance 0.51 Pain Relevance 0
HRT resulted also in a significant (P = 0.035) but less pronounced reduction in the other collagen type I degradation product, ICTP.
Gene_expression (degradation product) of degradation product
6) Confidence 0.00 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC546286 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox