INT122197

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Context Info
Confidence 0.42
First Reported 2004
Last Reported 2009
Negated 1
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.92
Pain Relevance 0.95

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B cells 2
skin 2
mast cells 2
IGHE (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 38 99.66 Very High Very High Very High
cINOD 10 96.08 Very High Very High Very High
Analgesic 1 75.08 Quite High
Inflammation 9 66.64 Quite High
chemokine 1 64.72 Quite High
cytokine 2 64.08 Quite High
psoriasis 1 50.40 Quite High
headache 1 10.00 Low Low
antagonist 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 11 95.36 Very High Very High Very High
Hypersensitivity 19 93.08 High High
Sprains And Strains 3 88.96 High High
Asthma 15 85.20 High High
Eczema 10 69.12 Quite High
Urticaria 53 67.64 Quite High
Staphylococcus Infection 3 53.00 Quite High
Psoriasis 1 50.40 Quite High
Disease 9 48.80 Quite Low
Eosinophilia 1 34.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the absence of an effect on IgE-secreting B cells and epsilon mRNA in nasal lavage fluid suggests that omalizumab treatment for 6 months does not significantly modulate synthesis of nasal IgE.


Regulation (effect) of Localization (secreting) of IgE in B cells
1) Confidence 0.42 Published 2004 Journal Ann. Allergy Asthma Immunol. Section Body Doc Link 15478383 Disease Relevance 0 Pain Relevance 0
Sera were analyzed retrospectively for IgE and histamine release (passive sensitization) to chlorhexidine.
Spec (analyzed) Regulation (retrospectively) of Localization (release) of IgE
2) Confidence 0.40 Published 2007 Journal J. Allergy Clin. Immunol. Section Body Doc Link 17559915 Disease Relevance 0.08 Pain Relevance 0
But, there was no significant association between the degree of colonization and the presence of serum IgE specific for staphylococcal superantigens (data not shown), suggesting that skin colonization of S. aureus could not affect on IgE sensitization to staphylococcal superantigens in AICU patients.
Neg (not) Regulation (affect) of Localization (sensitization) of IgE in skin
3) Confidence 0.28 Published 2008 Journal Journal of Korean Medical Science Section Body Doc Link PMC2580015 Disease Relevance 0.64 Pain Relevance 0.15
Aspirin and salicylates modulate IgE-mediated leukotriene secretion in mast cells through a dihydropyridine receptor-mediated Ca(2+) influx.
Regulation (modulate) of Localization (secretion) of IgE in mast cells associated with aspirin
4) Confidence 0.16 Published 2009 Journal Clin. Immunol. Section Title Doc Link 19144570 Disease Relevance 0.19 Pain Relevance 0.79

General Comments

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