INT122217

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Context Info
Confidence 0.52
First Reported 2002
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.08
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL1B, CCL5) aging (IL1B, CCL5) extracellular region (IL1B, CCL5)
cell-cell signaling (IL1B, CCL5) cytosol (IL1B) signal transduction (IL1B)
IL1B (Homo sapiens)
CCL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Snapping jaw 2 50.00 Quite Low
chemokine 11 35.80 Quite Low
metalloproteinase 6 10.36 Low Low
Inflammation 19 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
Freund adjuvant 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Temporomandibular Joint Disorders 1 77.40 Quite High
Temporomandibular Joint Syndrome 2 50.00 Quite Low
Disease 8 8.44 Low Low
INFLAMMATION 21 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increase in RANTES gene expression in response to IL-1beta was confirmed by PCR and real-time PCR.
IL-1beta Positive_regulation (increase) of Gene_expression (expression) of RANTES
1) Confidence 0.52 Published 2004 Journal J. Oral Pathol. Med. Section Body Doc Link 15482330 Disease Relevance 0.08 Pain Relevance 0
Indeed, TNF together with TWEAK increased the production of IP-10 69-fold and that of RANTES 46-fold, while IL-1 together with TWEAK enhanced RANTES production 35-fold.
IL-1 Positive_regulation (enhanced) of Gene_expression (production) of RANTES
2) Confidence 0.04 Published 2002 Journal Arthritis Res Section Body Doc Link PMC83846 Disease Relevance 0 Pain Relevance 0

General Comments

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