INT122237

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Context Info
Confidence 0.20
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gnrh1, Gh1) extracellular region (Gnrh1, Gh1) mitochondrion (Gh1)
cytosol (Gh1) signal transduction (Gh1) nucleus (Gh1)
Anatomy Link Frequency
plasma 1
Gnrh1 (Rattus norvegicus)
Gh1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 4 100.00 Very High Very High Very High
antagonist 4 83.12 Quite High
Intracerebroventricular 2 75.52 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In stimulated conditions, i.c.v. administration of CDP-choline (1 micromol, i.c.v.) produced an increase in clonidine-stimulated GH, thyrotyropin-releasing hormone (TRH)-stimulated TSH, LH-releasing hormone (LHRH)-stimulated LH, but not FSH levels.
LHRH Positive_regulation (increase) of GH associated with clonidine
1) Confidence 0.20 Published 2004 Journal Fundam Clin Pharmacol Section Abstract Doc Link 15482372 Disease Relevance 0 Pain Relevance 0.19
The results show that CDP-choline can increase plasma ACTH and produce additional increases in serum levels of TSH, GH and LH stimulated by TRH, clonidine and LHRH, respectively.
LHRH Positive_regulation (stimulated) of GH in plasma associated with clonidine
2) Confidence 0.09 Published 2004 Journal Fundam Clin Pharmacol Section Abstract Doc Link 15482372 Disease Relevance 0 Pain Relevance 0.24

General Comments

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