INT122268

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Context Info
Confidence 0.40
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grin2b, Grm5) embryo development (Grin2b) cytoplasm (Grm5)
signal transducer activity (Grm5)
Anatomy Link Frequency
neurons 1
Grin2b (Rattus norvegicus)
Grm5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dorsal horn neuron 1 99.96 Very High Very High Very High
intrathecal 1 99.12 Very High Very High Very High
spinal dorsal horn 4 95.76 Very High Very High Very High
Inflammation 10 94.08 High High
Hyperalgesia 4 93.04 High High
agonist 2 83.92 Quite High
nMDA receptor 3 75.00 Quite High
Glutamate receptor 3 75.00 Quite High
Dorsal horn 2 74.84 Quite High
Calcium channel 1 71.00 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 7 94.08 High High
Hyperalgesia 4 93.04 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Double immunofluorescence studies indicated that NR1 is colocalized with mGluR5 in dorsal horn neurons. mGluR5 also coimmunoprecipitates with NR2B.
NR2B Binding (coimmunoprecipitates) of mGluR5 in neurons associated with dorsal horn neuron
1) Confidence 0.40 Published 2004 Journal J. Neurosci. Section Abstract Doc Link 15483135 Disease Relevance 0.52 Pain Relevance 1.10

General Comments

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