INT122300

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Context Info
Confidence 0.59
First Reported 2004
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.07
Pain Relevance 1.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nqo1) oxidoreductase activity (Nqo1) cytoplasm (Nqo1)
Anatomy Link Frequency
spinal cord 2
Nqo1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 7 100.00 Very High Very High Very High
Neuropathic pain 6 100.00 Very High Very High Very High
intrathecal 2 91.16 High High
allodynia 3 89.32 High High
antagonist 2 83.20 Quite High
Eae 1 79.76 Quite High
Pain management 1 78.52 Quite High
Analgesic 3 75.00 Quite High
nMDA receptor 2 75.00 Quite High
Pain 1 67.92 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 10 100.00 Very High Very High Very High
Pain 3 78.08 Quite High
Hyperalgesia 1 67.24 Quite High
Nervous System Injury 1 63.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increase in NADPH diaphorase activity in the spinal cord associated with neuropathic pain was also blocked by these extracts.
Negative_regulation (blocked) of Positive_regulation (increase) of NADPH diaphorase in spinal cord associated with neuropathic pain and spinal cord
1) Confidence 0.59 Published 2004 Journal Neurosci. Lett. Section Abstract Doc Link 15488309 Disease Relevance 0.99 Pain Relevance 1.37
The enhancement of NADPH-diaphorase staining by NOR3 was significantly inhibited by CPTIO, an NO scavenger, ODQ, a soluble guanylate cyclase inhibitor, and KT5823, an inhibitor of cGMP-dependent protein kinase.
Negative_regulation (inhibited) of Positive_regulation (enhancement) of NADPH-diaphorase
2) Confidence 0.16 Published 2007 Journal Nitric Oxide Section Abstract Doc Link 17548218 Disease Relevance 0.08 Pain Relevance 0.46

General Comments

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