INT122349

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.64
First Reported 2005
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.55
Pain Relevance 3.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Trpv1) signal transduction (Ngf) extracellular space (Ngf)
aging (Ngf) extracellular region (Ngf) plasma membrane (Trpv1)
Anatomy Link Frequency
sensory neurons 1
Ngf (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 211 100.00 Very High Very High Very High
qutenza 115 100.00 Very High Very High Very High
Thermal hyperalgesia 7 99.04 Very High Very High Very High
IPN 1 97.16 Very High Very High Very High
trigeminal ganglion 118 87.00 High High
Eae 2 84.88 Quite High
Hyperalgesia 6 83.36 Quite High
dorsal root ganglion 24 82.40 Quite High
nociceptor 18 79.76 Quite High
Calcitonin gene-related peptide 192 79.28 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 15 99.04 Very High Very High Very High
Inflammatory Pain 1 97.16 Very High Very High Very High
Nociception 16 89.36 High High
Ganglion Cysts 146 87.00 High High
Injury 48 84.88 Quite High
INFLAMMATION 12 76.76 Quite High
Pain 7 71.08 Quite High
Hypersensitivity 4 52.08 Quite High
Headache 12 47.20 Quite Low
Disease 4 43.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, NGF has recently been shown to modulate TRPV1 by releasing the receptor from phosphotidylinositol-4,5-bisphosphate-mediated inhibition [27].
NGF Regulation (modulate) of TRPV1 associated with nerve growth factor
1) Confidence 0.64 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.88 Pain Relevance 1.54
Differential regulation of 3-beta-hydroxysteroid dehydrogenase and vanilloid receptor TRPV1 mRNA in sensory neurons by capsaicin and NGF.
NGF Regulation (regulation) of TRPV1 in sensory neurons associated with qutenza
2) Confidence 0.61 Published 2005 Journal Pharmacology Section Title Doc Link 15492487 Disease Relevance 0 Pain Relevance 0.87
NGF, GDNF or BDNF (100 ng/ml) did not significantly alter TRPV1 mRNA levels after 5 days of treatment (Fig. 4).
NGF Neg (not) Regulation (alter) of TRPV1 mRNA associated with nerve growth factor
3) Confidence 0.28 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC548274 Disease Relevance 0.20 Pain Relevance 0.28
NGF positively regulated transcriptional activity of both rTRPV1 promoter regions in PC12 cells.
NGF Regulation (regulated) of rTRPV1 associated with nerve growth factor
4) Confidence 0.23 Published 2007 Journal J. Neurochem. Section Abstract Doc Link 17217411 Disease Relevance 0.47 Pain Relevance 1.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox