INT122449

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Context Info
Confidence 0.67
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 10
Total Number 11
Disease Relevance 7.97
Pain Relevance 1.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (SMUG1) hydrolase activity, acting on glycosyl bonds (SMUG1) nucleolus (SMUG1)
nucleus (SMUG1) DNA binding (SMUG1)
Anatomy Link Frequency
liver 1
skeletal muscle 1
brain 1
parathyroid 1
parenchyma 1
SMUG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
isoflurane 9 95.36 Very High Very High Very High
imagery 258 91.20 High High
positron emission tomography 159 84.64 Quite High
Pain 1 65.04 Quite High
ischemia 12 52.44 Quite High
Inflammation 48 37.20 Quite Low
ketamine 5 17.00 Low Low
medulla 36 16.32 Low Low
fibrosis 12 13.24 Low Low
anesthesia 8 10.64 Low Low
Disease Link Frequency Relevance Heat
Cancer 372 100.00 Very High Very High Very High
Parathyroid Cancer 9 99.96 Very High Very High Very High
Disease 82 99.88 Very High Very High Very High
Metastasis 133 99.10 Very High Very High Very High
Breast Cancer 88 98.80 Very High Very High Very High
Recurrence 22 98.04 Very High Very High Very High
Fibroadenoma 1 98.04 Very High Very High Very High
Lung Cancer 21 96.48 Very High Very High Very High
Pneumonia 8 96.12 Very High Very High Very High
Non-small-cell Lung Cancer 20 93.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PET/CT helps in the differential diagnosis by enabling the exact localization of increased FDG uptake [20,22,35,36].
Localization (localization) of FDG
1) Confidence 0.67 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 1.37 Pain Relevance 0.07
Studies demonstrated that the decrease of FDG uptake after a single infusion of chemotherapy was a predictor of eventual response to this regimen [80].
Localization (decrease) of FDG
2) Confidence 0.63 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.87 Pain Relevance 0.10
One limitation is cerebral metastasis, because the brain shows the highest normal FDG accumulation.
Localization (accumulation) of FDG in brain associated with metastasis
3) Confidence 0.63 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.98 Pain Relevance 0.07
Similarly, no decrease of tumor FDG uptake after the first infusion was a predictor of non-response.
Localization (decrease) of FDG associated with cancer
4) Confidence 0.63 Published 2010 Journal The Yale Journal of Biology and Medicine Section Body Doc Link PMC2892773 Disease Relevance 0.96 Pain Relevance 0.09
Nonetheless, their data did demonstrate a trend between decreasing total FDG accumulation and decreasing tumor burden with an increase in recurrences.
Localization (accumulation) of FDG associated with cancer and recurrence
5) Confidence 0.45 Published 2007 Journal Mol Imaging Biol Section Body Doc Link PMC2040178 Disease Relevance 0.90 Pain Relevance 0.12
To date, both 99mTc-MIBI and FDG-PET are useful to localize parathyroid tumors.
Localization (localize) of FDG-PET in parathyroid associated with parathyroid cancer
6) Confidence 0.19 Published 2004 Journal Intern. Med. Section Abstract Doc Link 15497517 Disease Relevance 1.32 Pain Relevance 0.22
As expected, brain and heart showed high degrees of FDG accumulation, while liver and skeletal muscle experienced less (Fig. 2a).
Localization (accumulation) of FDG in skeletal muscle
7) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2917372 Disease Relevance 0 Pain Relevance 0.11
In benign disease, 18F-FDG and 99mTc-MIBI did not localize fibrocystic lesions, but could falsely identify fibroadenomas as cancer.
Neg (not) Localization (localize) of FDG associated with cancer, fibroadenoma and disease
8) Confidence 0.09 Published 2005 Journal Breast Cancer Res Section Body Doc Link PMC1175073 Disease Relevance 0.88 Pain Relevance 0.10
Acquisition started 3 h after FDG-injection to reduce tracer uptake in the kidneys caused by renal excretion of FDG.
Localization (excretion) of FDG
9) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2669171 Disease Relevance 0.38 Pain Relevance 0.41
Micro-autoradiographic quantification of FDG-uptake of renal parenchyma
Localization (quantification) of FDG in parenchyma
10) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2669171 Disease Relevance 0.32 Pain Relevance 0.07
As expected, brain and heart showed high degrees of FDG accumulation, while liver and skeletal muscle experienced less (Fig. 2a).
Localization (accumulation) of FDG in liver
11) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2917372 Disease Relevance 0 Pain Relevance 0.11

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