INT122497

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Context Info
Confidence 0.58
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.80
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (UBE2S) cell cycle (UBE2S) cell division (UBE2S)
ligase activity (UBE2S)
UBE2S (Homo sapiens)
Pain Link Frequency Relevance Heat
tetrodotoxin 7 96.48 Very High Very High Very High
sodium channel 2 79.68 Quite High
Inflammation 3 70.96 Quite High
Inflammatory response 1 57.12 Quite High
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 4 94.88 High High
Adhesions 1 93.48 High High
Reprotox - General 1 1 77.12 Quite High
Neurological Disease 1 76.00 Quite High
INFLAMMATION 4 70.96 Quite High
Hepatitis 6 67.28 Quite High
Hepatitis E Virus Infection 7 50.00 Quite Low
Viral Infection 4 26.00 Quite Low
Shock 1 12.28 Low Low
Gastroenteritis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using Affymetrix GeneChip (HG-U133A), we have selected a subset of 692 differentially expressed genes, several of which are-cullin 4A (CUL4A), ubiquitin carrier protein (E2-EPF), proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) (PSMB8), protein tyrosine phosphatase type IVA (PTP4A1), intercellular adhesion molecule 1 (ICAM1), prostaglandin-endoperoxide synthase 2 (PTGS2), and caspase 1 (CASP1).
Gene_expression (expressed) of E2-EPF associated with adhesions
1) Confidence 0.58 Published 2004 Journal Toxicon Section Abstract Doc Link 15501285 Disease Relevance 0.68 Pain Relevance 0.64
Taken together the presence of neutralizing antibody binding sites of HEV on E2s, and the shape of the dimer, we suggest that E2s is present on the surface protrusions of HEV shown in the electron microscopic structure [5].
Gene_expression (present) of E2s
2) Confidence 0.02 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2714988 Disease Relevance 0.12 Pain Relevance 0

General Comments

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