INT122525

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Context Info
Confidence 0.58
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.76
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (FOXO1) nucleoplasm (FOXO1) nucleus (FOXO1)
embryo development (FOXO1) transcription factor binding (FOXO1) cytoplasm (FOXO1)
FOXO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 9 99.84 Very High Very High Very High
pain pelvic 2 93.88 High High
Pain 1 86.00 High High
Inflammatory response 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 8 99.84 Very High Very High Very High
Alveolar Rhabdomyosarcoma 2 96.00 Very High Very High Very High
Breast Cancer 1 94.48 High High
Lymphatic System Cancer 2 94.40 High High
Disease 3 94.36 High High
Reprotox - General 3 8 93.88 High High
Rhabdomyosarcoma 2 92.48 High High
Solid Tumor 1 87.76 High High
Pain 1 86.00 High High
INFLAMMATION 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FOXO1 and c-jun transcription factors mRNA are modulated in endometriosis.
Regulation (modulated) of FOXO1 associated with endometriosis
1) Confidence 0.58 Published 2004 Journal Mol. Hum. Reprod. Section Title Doc Link 15501904 Disease Relevance 0.97 Pain Relevance 0.36
The patient was positive for the PAX3-FKHR fusion gene.
Regulation (positive) of FKHR
2) Confidence 0.44 Published 2008 Journal J Clin Exp Hematop Section Abstract Doc Link 19039198 Disease Relevance 0.69 Pain Relevance 0.09
Of interest, also, is the up-regulation of FOXO1A (2.1-fold) in ESE vs.
Regulation (regulation) of FOXO1A
3) Confidence 0.36 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1775064 Disease Relevance 0.09 Pain Relevance 0

General Comments

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