INT122542

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Context Info
Confidence 0.62
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.09
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (FGF2, IL6) extracellular region (FGF2, IL6) signal transduction (FGF2)
aging (IL6) nucleus (FGF2) cytoplasm (FGF2)
Anatomy Link Frequency
Fibroblast 2
FGF2 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 94.28 High High
Disease Link Frequency Relevance Heat
Pancreatitis 3 94.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: FGF-2 induced IL-6 release in a dose- and time-dependent manner.
FGF-2 Positive_regulation (induced) of Localization (release) of IL-6
1) Confidence 0.62 Published 2004 Journal Pancreas Section Body Doc Link 15502643 Disease Relevance 0 Pain Relevance 0
Fibroblast growth factor-2 stimulates interleukin-6 secretion in human pancreatic periacinar myofibroblasts.
Fibroblast growth factor-2 Positive_regulation (stimulates) of Localization (secretion) of interleukin-6 in Fibroblast
2) Confidence 0.62 Published 2004 Journal Pancreas Section Title Doc Link 15502643 Disease Relevance 0.09 Pain Relevance 0.09
FGF-2 rapidly induced activation of ERK1/2 and p38 MAP kinases, and specific inhibitors for these enzymes significantly reduced FGF-2-induced IL-6 release.
FGF-2 Positive_regulation (induced) of Localization (release) of IL-6
3) Confidence 0.45 Published 2004 Journal Pancreas Section Body Doc Link 15502643 Disease Relevance 0 Pain Relevance 0

General Comments

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