INT122713

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.16
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RTCA) extracellular region (Guca2b) RNA binding (RTCA)
nucleus (RTCA) ligase activity (RTCA)
Guca2b (Rattus norvegicus)
RTCA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 2 93.08 High High
imagery 1 28.56 Quite Low
spastic colon 1 25.00 Low Low
antagonist 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Diarrhoea 2 98.44 Very High Very High Very High
Natriuresis 1 61.44 Quite High
Cancer 1 44.08 Quite Low
Colon Cancer 3 40.64 Quite Low
Functional Bowel Disorder 1 25.00 Low Low
Hypertension 1 25.00 Low Low
Respiratory Disease 1 25.00 Low Low
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

1 25.00 Low Low
Constipation 1 25.00 Low Low
Asthma 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Guanylin, uroguanylin, and microbial ST peptides activate a common apical membrane receptor-guanylate cyclase (R-GC) that elicits large increases in the intestinal secretion of chloride and bicarbonate via the intracellular second messenger, cGMP.
uroguanylin Positive_regulation (activate) of cyclase
1) Confidence 0.03 Published 2004 Journal Pharmacol. Ther. Section Abstract Doc Link 15518884 Disease Relevance 0.16 Pain Relevance 0.05

General Comments

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