INT122740

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Context Info
Confidence 0.58
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.68
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cd55)
Anatomy Link Frequency
colon 2
Cd55 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 2 78.00 Quite High
antagonist 1 57.60 Quite High
anesthesia 5 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 10 98.64 Very High Very High Very High
Mesothelioma 79 96.72 Very High Very High Very High
Hypoxia 61 86.24 High High
Metastasis 6 85.84 High High
Cancer 62 84.96 Quite High
Malignant Neoplastic Disease 10 78.44 Quite High
INFLAMMATION 2 76.56 Quite High
Pressure And Volume Under Development 10 66.44 Quite High
Severe Combined Immunodeficiency 4 62.92 Quite High
Edema 33 58.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The complement regulatory protein decay-accelerating factor (DAF or CD55) was induced following PGE(2) treatment of LS174T colon cancer cells.
Positive_regulation (induced) of protein decay-accelerating factor in colon associated with colon cancer
1) Confidence 0.58 Published 2005 Journal J. Biol. Chem. Section Abstract Doc Link 15520008 Disease Relevance 0.67 Pain Relevance 0.08
The complement regulatory protein decay-accelerating factor (DAF or CD55) was induced following PGE(2) treatment of LS174T colon cancer cells.
Positive_regulation (induced) of CD55 in colon associated with colon cancer
2) Confidence 0.48 Published 2005 Journal J. Biol. Chem. Section Abstract Doc Link 15520008 Disease Relevance 0.67 Pain Relevance 0.08
All cell cultures were more than 90% positive for CD47, CD55 and CD99, between 65 and 95% for CD90 and CD46, between 30 and 92% for CD56 and CD63, between 5 and 60% for CD140b, between 0 and 20% for CD141.
Positive_regulation (positive) of CD55
3) Confidence 0.21 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2850899 Disease Relevance 0.92 Pain Relevance 0.03
Analysis of lipid microdomains showed a decrease of caveolin-1 and AQP1 (markers of caveolae), and an increase in CD55 (marker of lipid rafts).
Positive_regulation (increase) of CD55
4) Confidence 0.09 Published 2006 Journal Respir Res Section Abstract Doc Link PMC1363731 Disease Relevance 0.42 Pain Relevance 0

General Comments

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