INT122749

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Context Info
Confidence 0.07
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Cyp3a23/3a1, Akt1) nucleoplasm (Akt1) transport (Akt1)
endoplasmic reticulum (Cyp3a23/3a1) enzyme binding (Akt1) carbohydrate metabolic process (Akt1)
Cyp3a23/3a1 (Rattus norvegicus)
Akt1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 2 87.80 High High
gABA 4 77.32 Quite High
dexamethasone 2 75.00 Quite High
GABAergic 1 75.00 Quite High
anesthesia 1 65.36 Quite High
Disease Link Frequency Relevance Heat
Heart Rate Under Development 2 84.76 Quite High
Hypertension 3 84.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, Dex induced an association of GR with the regulatory subunit of PI3K, p85alpha, in a ligand-dependent manner and promoted serine/threonine kinase Akt phosphorylation that was blocked by coadministration of mifepristone or LY294002.
Dex Positive_regulation (promoted) of Phosphorylation (phosphorylation) of Akt
1) Confidence 0.07 Published 2005 Journal Mol. Pharmacol. Section Abstract Doc Link 15523051 Disease Relevance 0.24 Pain Relevance 0.41

General Comments

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