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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (TH) cytosol (TH) mitochondrion (TH)
small molecule metabolic process (TH) nucleus (TH) cellular nitrogen compound metabolic process (TH)
Anatomy Link Frequency
brainstem 2
TH (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 7 99.96 Very High Very High Very High
Thalamus 1 98.28 Very High Very High Very High
Neuropeptide 1 96.44 Very High Very High Very High
Neurotransmitter 1 94.64 High High
substance P 2 92.48 High High
Enkephalin 2 90.24 High High
Dorsal column 1 79.68 Quite High
peripheral neuropathy 1 79.44 Quite High
Substantia nigra 1 38.96 Quite Low
Dopamine 1 32.64 Quite Low
Disease Link Frequency Relevance Heat
Stress 1 89.84 High High
Dystonia 2 82.00 Quite High
Dysphagia 1 81.04 Quite High
Deafness 1 80.20 Quite High
Peripheral Neuropathy 1 79.44 Quite High
Freckles 2 75.00 Quite High
Congenital Anomalies 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the brainstem, immunoreactivity for tyrosine hydroxylase, tryptophan hydroxylase, and calbindin-D28K was severely reduced throughout the brainstem in all the XPA cases.
Negative_regulation (reduced) of Regulation (immunoreactivity) of tyrosine hydroxylase in brainstem associated with medulla
1) Confidence 0.03 Published 2004 Journal J. Neuropathol. Exp. Neurol. Section Abstract Doc Link 15535132 Disease Relevance 0.56 Pain Relevance 0.63

General Comments

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