INT123139

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 1.98
Pain Relevance 2.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp3) extracellular space (Mmp3) extracellular region (Mmp3)
proteinaceous extracellular matrix (Mmp3) nucleus (Mmp3) protein complex (Mmp3)
Anatomy Link Frequency
cleavage 1
Mmp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 34 100.00 Very High Very High Very High
spinal inflammation 16 100.00 Very High Very High Very High
Migraine 11 98.88 Very High Very High Very High
headache 1 83.56 Quite High
endometriosis 2 50.00 Quite Low
Dismenorea 2 50.00 Quite Low
nMDA receptor 42 5.00 Very Low Very Low Very Low
Spinal cord 17 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Low Back Pain 16 100.00 Very High Very High Very High
Headache 11 98.88 Very High Very High Very High
Primary Headache Disorders 1 83.92 Quite High
Dysmenorrhea 2 50.00 Quite Low
Endometriosis (extended) 2 50.00 Quite Low
Death 3 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OBJECTIVE: To study the linkage and association of ankylosing spondylitis (AS) with genotypes for matrix metalloproteinase 3 (MMP3), a gene located at chromosome 11q22.3 and lying within the 101-124 cM region observed in a recent genome-wide scan as a region associated with AS susceptibility.
matrix metalloproteinase 3 Binding (association) of associated with spinal inflammation and metalloproteinase
1) Confidence 0.37 Published 2005 Journal Rheumatology (Oxford) Section Abstract Doc Link 15546966 Disease Relevance 0.37 Pain Relevance 0.46
Lack of association of matrix metalloproteinase 3 (MMP3) genotypes with ankylosing spondylitis susceptibility and severity.
matrix metalloproteinase 3 Binding (association) of associated with spinal inflammation and metalloproteinase
2) Confidence 0.37 Published 2005 Journal Rheumatology (Oxford) Section Title Doc Link 15546966 Disease Relevance 0.29 Pain Relevance 0.47
OBJECTIVE: To study the linkage and association of ankylosing spondylitis (AS) with genotypes for matrix metalloproteinase 3 (MMP3), a gene located at chromosome 11q22.3 and lying within the 101-124 cM region observed in a recent genome-wide scan as a region associated with AS susceptibility.
MMP3 Binding (association) of associated with spinal inflammation and metalloproteinase
3) Confidence 0.37 Published 2005 Journal Rheumatology (Oxford) Section Abstract Doc Link 15546966 Disease Relevance 0.37 Pain Relevance 0.46
Lack of association of matrix metalloproteinase 3 (MMP3) genotypes with ankylosing spondylitis susceptibility and severity.
MMP3 Binding (association) of associated with spinal inflammation and metalloproteinase
4) Confidence 0.37 Published 2005 Journal Rheumatology (Oxford) Section Title Doc Link 15546966 Disease Relevance 0.29 Pain Relevance 0.47
of the NR1 subunit may by important for sequence-specific cleavage by MMP-3.
MMP-3 Binding (cleavage) of in cleavage
5) Confidence 0.27 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2443283 Disease Relevance 0 Pain Relevance 0
CONCLUSION: Individuals with the MMP-1 2G allelotype have significantly increased risk of developing EM and adenomyosis; MMP-3 promoter SNP is not associated with susceptibility to EM and adenomyosis, 2G/6A haplotype could be used as a stratified marker for EM.


MMP-3 promoter SNP Binding (associated) of
6) Confidence 0.16 Published 2005 Journal Zhonghua Fu Chan Ke Za Zhi Section Body Doc Link 16202315 Disease Relevance 0 Pain Relevance 0
This is the first study to evaluate the association between MMP-3 and ACE polymorphisms, and migraine.
MMP-3 Binding (association) of associated with migraine and metalloproteinase
7) Confidence 0.13 Published 2007 Journal Cephalalgia Section Abstract Doc Link 17381556 Disease Relevance 0.66 Pain Relevance 0.98

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox