INT123177

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Context Info
Confidence 0.70
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.37
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gast)
Anatomy Link Frequency
muscle 2
stomach 2
Gast (Mus musculus)
Pain Link Frequency Relevance Heat
halothane 38 85.44 High High
cINOD 4 50.00 Quite Low
Action potential 4 35.36 Quite Low
peptic ulcer disease 2 33.28 Quite Low
isoflurane 38 5.00 Very Low Very Low Very Low
gABA 26 5.00 Very Low Very Low Very Low
nMDA receptor 24 5.00 Very Low Very Low Very Low
agonist 14 5.00 Very Low Very Low Very Low
potassium channel 6 5.00 Very Low Very Low Very Low
analgesia 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 22 99.88 Very High Very High Very High
Helicobacter Infection 2 99.28 Very High Very High Very High
Frailty 4 98.68 Very High Very High Very High
Ulcers 6 94.92 High High
Infection 4 88.96 High High
Injury 2 50.00 Quite Low
INFLAMMATION 2 50.00 Quite Low
Stomach Cancer 2 44.24 Quite Low
Ganglion Cysts 2 13.76 Low Low
Unconsciousness 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of glycine-extended gastrin inhibits parietal cell loss and atrophy in the mouse stomach.
Positive_regulation (Overexpression) of Gene_expression (Overexpression) of gastrin in stomach associated with frailty
1) Confidence 0.70 Published 2004 Journal Cancer Res. Section Title Doc Link 15548680 Disease Relevance 0.69 Pain Relevance 0
Transgenic mice overexpressing amidated gastrin (INS-GAS mice), G-gly (MTI/G-gly mice), and both peptides (INS-GAS/G-gly mice) were used for assessment of acid secretion and ulcer susceptibility and histologic examination and scoring of preneoplastic lesions in response to the 3 and 6 months Helicobacter felis (H. felis) infection.
Positive_regulation (overexpressing) of Gene_expression (overexpressing) of gastrin associated with targeted disruption, ulcers and infection
2) Confidence 0.47 Published 2004 Journal Cancer Res. Section Abstract Doc Link 15548680 Disease Relevance 0.69 Pain Relevance 0
Use of NSAIDs should increase suspicion of cryptic GAS infection in patients with increasing pain at sites of nonpenetrating muscle injury.


Positive_regulation (increase) of Gene_expression (infection) of GAS in muscle
3) Confidence 0.41 Published 2008 Journal J. Infect. Dis. Section Body Doc Link 18939933 Disease Relevance 0 Pain Relevance 0
On application of pressures up to 274 atm by increasing the amount of helium (a non-anaesthetic gas at these pressures) in the container, these changes were reversed: S?
Positive_regulation (increasing) of Gene_expression (anaesthetic) of gas
4) Confidence 0.14 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989583 Disease Relevance 0 Pain Relevance 0.04
On application of pressures up to 274 atm by increasing the amount of helium (a non-anaesthetic gas at these pressures) in the container, these changes were reversed: S?
Positive_regulation (increasing) of Gene_expression (pressures) of gas
5) Confidence 0.14 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989583 Disease Relevance 0 Pain Relevance 0.04

General Comments

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