INT123180

Context Info Confidence 0.01 First Reported 2004 Last Reported 2004 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.61 Pain Relevance 0.14

endosome (Lamtor1) cell differentiation (Bmp6) extracellular space (Bmp6) growth (Bmp6) extracellular region (Bmp6) Golgi apparatus (Lamtor1)

Bmp6 (Rattus norvegicus) Lamtor1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat antagonist 2 96.88 Pain 1 55.52

Disease Link Frequency Relevance Heat Reprotox - General 1 5 100.00 Metastasis 3 91.92 Osteoporosis 1 82.88

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Addition of exogenous BMP-6 to DU-145 prostate cancer cell cultures inhibited their growth by up-regulation of several cyclin-dependent kinase inhibitors such as p21/CIP, p18, and p19.

BMP-6 Positive_regulation (up-regulation) of p18 associated with reprotox - general 1

1) Confidence 0.01 Published 2004 Journal Cancer Res. Section Abstract Doc Link 15548695 Disease Relevance 0.61 Pain Relevance 0.14

General Comments

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