INT123229

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Context Info
Confidence 0.30
First Reported 2004
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (PRL) cytosol (PRL) extracellular region (PRL)
plasma membrane (OXTR) signal transducer activity (OXTR)
OXTR (Homo sapiens)
PRL (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 33 100.00 Very High Very High Very High
Opioid 3 100.00 Very High Very High Very High
substance P 2 100.00 Very High Very High Very High
Dopamine 63 90.72 High High
Neuropeptide 2 83.04 Quite High
GABAergic 1 76.88 Quite High
gABA 13 68.16 Quite High
Raphe 1 63.60 Quite High
Kinase C 1 37.60 Quite Low
Somatostatin 2 31.24 Quite Low
Disease Link Frequency Relevance Heat
Galactorrhea 124 5.00 Very Low Very Low Very Low
Reprotox - General 1 28 5.00 Very Low Very Low Very Low
Schizophrenia 20 5.00 Very Low Very Low Very Low
Psychosis 17 5.00 Very Low Very Low Very Low
Depression 9 5.00 Very Low Very Low Very Low
Reprotox - General 2 7 5.00 Very Low Very Low Very Low
Gynecomastia 7 5.00 Very Low Very Low Very Low
Hypertension 6 5.00 Very Low Very Low Very Low
Vomiting 4 5.00 Very Low Very Low Very Low
Eating Disorder 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Oxytocin, serotonin, opioids, histamine, substance P, and arginine-leucine modulate prolactin release by means of an autocrine/paracrine mechanism, whereas estrogen and progesterone hormones can act at the hypothalamic and adenohypophysial levels.
Oxytocin Regulation (modulate) of Localization (release) of prolactin associated with opioid, serotonin and substance p
1) Confidence 0.30 Published 2004 Journal Obstet. Gynecol. Clin. North Am. Section Abstract Doc Link 15550345 Disease Relevance 0 Pain Relevance 0.20
Oxytocin seems to participate in VIP-induced prolactin release and may act through the inhibition of TIDA.
Oxytocin Spec (seems) Regulation (participate) of Localization (release) of prolactin
2) Confidence 0.03 Published 2007 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2376090 Disease Relevance 0 Pain Relevance 0.53

General Comments

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