INT123301

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Context Info
Confidence 0.21
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Car2) mitochondrion (Creb1) extracellular space (Car2)
lyase activity (Car2) nucleus (Creb1) DNA binding (Creb1)
Car2 (Mus musculus)
Creb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 5 94.80 High High
antidepressant 3 89.80 High High
fluoxetine 5 82.72 Quite High
Desipramine 5 81.12 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 7 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CREB can be activated by both protein kinase A and by Ca2+-calmodulin-dependent protein kinases (CaMKs), which are in turn phosphorylated by their upstream activators CaMKKalpha and CaMMKKbeta.
Ca2 Positive_regulation (activated) of CREB
1) Confidence 0.21 Published 2004 Journal Neuropharmacology Section Abstract Doc Link 15555640 Disease Relevance 0.28 Pain Relevance 0.61

General Comments

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