INT123302

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Context Info
Confidence 0.44
First Reported 2004
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.10
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ceacam1) cell adhesion (Ceacam1) plasma membrane (Ceacam1)
Anatomy Link Frequency
extracellular matrix 2
Ceacam1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 9 100.00 Very High Very High Very High
metalloproteinase 7 100.00 Very High Very High Very High
agonist 5 84.40 Quite High
anesthesia 3 82.32 Quite High
Pain 2 80.28 Quite High
nociceptor 3 75.00 Quite High
adenocard 1 62.72 Quite High
ketamine 1 59.68 Quite High
Bioavailability 5 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Respiratory Syncytial Virus 116 99.88 Very High Very High Very High
Obesity 3 86.40 High High
Osteoporosis 10 85.92 High High
Osteogenic Sarcomas 1 49.28 Quite Low
Cancer 11 46.12 Quite Low
Osteomyelitis 1 44.96 Quite Low
Injury 1 44.36 Quite Low
Scoliosis 1 20.80 Low Low
Hypercalcemia 15 5.00 Very Low Very Low Very Low
Apoptosis 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Samples of the culture medium were analyzed for the presence of osteocalcin using a radioimmunoassay kit (Biomedical Technologies Inc.
Spec (analyzed) Positive_regulation (analyzed) of Spec (analyzed) Gene_expression (presence) of osteocalcin
1) Confidence 0.44 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2782207 Disease Relevance 0 Pain Relevance 0.10
The expression of type I collagen, osteocalcin and MMPs 2 and 13 increased toward week 2 and decreased thereafter, whereas the expression of MMP 8 was the highest on day 1.
Positive_regulation (increased) of Gene_expression (expression) of osteocalcin associated with metalloproteinase
2) Confidence 0.36 Published 2008 Journal Anatomical record (Hoboken, N.J. : 2007) Section Abstract Doc Link 18615687 Disease Relevance 0 Pain Relevance 0.37
The selective ecto-ATPase inhibitor, ARL-67156 (100, 200 microM) and suramin (100, 200 microM), an ecto-nucleotidase inhibitor as well as a P2 receptor antagonist, produced an increase in baseline and distension-induced discharge.
Positive_regulation (increase) of Gene_expression (produced) of ecto-ATPase associated with antagonist
3) Confidence 0.12 Published 2004 Journal Neuropharmacology Section Abstract Doc Link 15555643 Disease Relevance 0 Pain Relevance 0.40
ADSCs mineralize their extracellular matrix (ECM) and show increased expression of osteocalcin and alkaline phosphatase (ALP).[12] These factors may make ADSCs a viable clinical alternative to BMSCs.
Positive_regulation (increased) of Gene_expression (expression) of osteocalcin in extracellular matrix
4) Confidence 0.12 Published 2008 Journal Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India Section Body Doc Link PMC2739564 Disease Relevance 0.19 Pain Relevance 0.16
M RSV, the expression of osteogenic markers such as vitamin D3 receptor (VD3R), osteocalcin, osteopontin (OPN), and alkaline phosphatase (ALP) was upregulated relative to cells not treated with PDM02 or RSV (Fig. 5).
Positive_regulation (upregulated) of Gene_expression (expression) of osteocalcin associated with respiratory syncytial virus
5) Confidence 0.07 Published 2010 Journal Calcif Tissue Int Section Body Doc Link PMC2964465 Disease Relevance 0.90 Pain Relevance 0

General Comments

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