INT123337

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Context Info
Confidence 0.13
First Reported 2004
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.57
Pain Relevance 1.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cpox, Cpox) oxidoreductase activity (Cpox, Cpox) cytoplasm (Cpox, Cpox)
Anatomy Mention Frequency
DRG 2
Cpox (Mus musculus)
Cpox (Mus musculus)
Pain Term Frequency Confidence Heat
aspirin 52 98.76 Very High Very High Very High
Spinal cord 4 97.68 Very High Very High Very High
Lasting pain 4 96.72 Very High Very High Very High
Inflammation 12 96.04 Very High Very High Very High
Arthritis 3 91.48 High High
COX-2 inhibitor 3 90.68 High High
Analgesic 3 87.28 High High
cINOD 22 80.00 Quite High
Pain 12 76.08 Quite High
Peripheral nervous system 2 74.08 Quite High
Disease Term Frequency Confidence Heat
Asthma 25 98.04 Very High Very High Very High
Pain 14 96.72 Very High Very High Very High
INFLAMMATION 15 96.04 Very High Very High Very High
Arthritis 3 91.48 High High
Nociception 8 75.00 Quite High
Hyperalgesia 2 31.80 Quite Low
Bronchospasm 1 5.00 Very Low Very Low Very Low
Nasal Obstruction 1 5.00 Very Low Very Low Very Low
Respiratory Sounds 1 5.00 Very Low Very Low Very Low
Nasal Polyps 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together, these data support a role for COX-1 and perhaps COX-1v, not COX-2, as the primary producers of PGs in mouse DRG in normal and in mice subject to chronic pain and inflammation.
COX Regulation (role) of COX in DRG associated with inflammation and lasting pain
1) Confidence 0.13 Published 2004 Journal Prostaglandins Other Lipid Mediat. Section Abstract Doc Link 15560114 Disease Relevance 0.65 Pain Relevance 0.82
Together, these data support a role for COX-1 and perhaps COX-1v, not COX-2, as the primary producers of PGs in mouse DRG in normal and in mice subject to chronic pain and inflammation.
COX Regulation (role) of COX in DRG associated with inflammation and lasting pain
2) Confidence 0.11 Published 2004 Journal Prostaglandins Other Lipid Mediat. Section Abstract Doc Link 15560114 Disease Relevance 0.65 Pain Relevance 0.82
COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma

Cyclooxygenase (COX) -1 and COX-2 are expressed in airway cells, where their activities influence functions such as airway hyperreactivity.

COX Neg (not) Regulation (regulates) of COX associated with asthma and aspirin
3) Confidence 0.01 Published 2008 Journal FASEB J Section Title Doc Link PMC2691413 Disease Relevance 0.28 Pain Relevance 0.30

General Comments

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