INT123416

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Context Info
Confidence 0.60
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) plasma membrane (Oprm1) nucleus (Sp1)
intracellular (Sp1) DNA binding (Sp1) transcription factor binding (Sp1)
Sp1 (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 10 100.00 Very High Very High Very High
Morphine 2 86.72 High High
Analgesic 1 61.20 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In SL2 cells that lack endogenous Sp1 expression, B6 and CXBK MOR promoters demonstrated equal activity, whereas overexpression of Sp1 in SL2 cells enhanced B6 MOR promoter activity better than the CXBK promoter.
Gene_expression (overexpression) of Sp1 Positive_regulation (enhanced) of B6 MOR promoter associated with opioid receptor
1) Confidence 0.60 Published 2004 Journal Mol. Pharmacol. Section Abstract Doc Link 15562256 Disease Relevance 0 Pain Relevance 0.63

General Comments

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