INT123463

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Context Info
Confidence 0.37
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.25
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (ATP5G3) transport (ATP5G3) mitochondrion (ATP5G3)
aging (ATP5G3)
ATP5G3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid receptor 1 1 99.72 Very High Very High Very High
opiate 4 98.72 Very High Very High Very High
Opioid 2 97.40 Very High Very High Very High
Anterior cingulate cortex 2 86.24 High High
amygdala 1 75.00 Quite High
Morphine 1 75.00 Quite High
Pain 14 63.28 Quite High
midbrain 2 52.12 Quite High
deep brain stimulation 1 47.12 Quite Low
positron emission tomography 12 34.40 Quite Low
Disease Link Frequency Relevance Heat
Necrosis 3 98.24 Very High Very High Very High
Persistent Vegetative State 135 98.16 Very High Very High Very High
Cancer 15 97.88 Very High Very High Very High
Sleep Disorders 104 89.20 High High
Autoimmune Disease 7 82.20 Quite High
Coma 14 77.12 Quite High
Skin Cancer 44 67.68 Quite High
Cognitive Disorder 40 67.32 Quite High
Renal Cancer 5 66.64 Quite High
Pain 13 63.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BACKGROUND: We have identified a novel mu opiate receptor, p3, which is expressed in several human tissues, is selective for opiate alkaloids, insensitive to opioid peptides, and also is coupled to constitutive nitric oxide release.
Gene_expression (expressed) of p3 associated with opioid receptor 1, opiate and opioid
1) Confidence 0.37 Published 2004 Journal Med. Sci. Monit. Section Abstract Doc Link 15567973 Disease Relevance 0 Pain Relevance 0.57
Mismatch negativity (MMN) and P3, ERP components accompanying higher order processing have also been detected in a number of patients [21]; however, none of these components are clear indicators of conscious awareness.
Gene_expression (detected) of P3
2) Confidence 0.21 Published 2007 Journal Philos Ethics Humanit Med Section Body Doc Link PMC2245970 Disease Relevance 0.92 Pain Relevance 0.14
The realtime PCR approach was also employed to evaluate the expression of the two EPOR alleles of primary cultures of CEPs (P1, P3 and P5 patients).
Gene_expression (expression) of P3
3) Confidence 0.05 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2916842 Disease Relevance 0.06 Pain Relevance 0
Tregs also express a characteristic intracellular nuclear transcription regulator, forkhead box p3 (Foxp3) [25,26].
Gene_expression (express) of p3
4) Confidence 0.04 Published 2010 Journal J Transl Med Section Body Doc Link PMC2936304 Disease Relevance 0.98 Pain Relevance 0
Consistent with this idea, Gosselin and colleagues [35] found that both novel and target P3 were reduced in amplitude after 36 hours of waking, and that performance on attention-demanding tasks was deteriorated.
Gene_expression (reduced) of P3
5) Confidence 0.04 Published 2007 Journal Cell Mol Life Sci Section Body Doc Link PMC2778638 Disease Relevance 0.29 Pain Relevance 0.04

General Comments

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