INT123492

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Context Info
Confidence 0.00
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CCL4) extracellular space (CCL4) extracellular region (CCL4)
cell adhesion (CCL4) nucleus (TIAF1) molecular_function (TIAF1)
Anatomy Link Frequency
THP-1 3
monocytes 1
TIAF1 (Homo sapiens)
CCL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 10 100.00 Very High Very High Very High
chemokine 4 100.00 Very High Very High Very High
Inflammation 8 90.92 High High
Inflammatory response 2 72.16 Quite High
cINOD 2 68.20 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 10 90.92 High High
Disease 10 75.68 Quite High
Alzheimer's Dementia 4 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Curcumin abrogated Abeta1-40-induced expression of cytokines (TNF-alpha and IL-1beta) and chemokines (MIP-1beta, MCP-1 and IL-8) in both peripheral blood monocytes and THP-1 cells.
Abeta1-40-induced Positive_regulation (induced) of Gene_expression (expression) of MIP-1beta in THP-1 associated with chemokine and cytokine
1) Confidence 0.00 Published 2004 Journal J. Neurochem. Section Abstract Doc Link 15569263 Disease Relevance 0.73 Pain Relevance 0.40
Curcumin abrogated Abeta1-40-induced expression of cytokines (TNF-alpha and IL-1beta) and chemokines (MIP-1beta, MCP-1 and IL-8) in both peripheral blood monocytes and THP-1 cells.
Abeta1-40-induced Positive_regulation (induced) of in monocytes Gene_expression (expression) of MIP-1beta in THP-1 associated with chemokine and cytokine
2) Confidence 0.00 Published 2004 Journal J. Neurochem. Section Abstract Doc Link 15569263 Disease Relevance 0.73 Pain Relevance 0.40

General Comments

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