INT123518

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Context Info
Confidence 0.06
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Aktip) plasma membrane (Aktip) cytoplasm (Aktip)
Aktip (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 5 50.00 Quite Low
aspirin 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 50.00 Quite Low
Prostatic Intraepithelial Neoplasia 1 50.00 Quite Low
Adenocarcinoma 1 50.00 Quite Low
Targeted Disruption 1 50.00 Quite Low
Toxicity 1 10.44 Low Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Colon Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Down-regulation of AKT protein (total and phosphorylated at Ser473) signaling by celecoxib clearly indicates an inhibition of the survival gene and the pathological process that could otherwise lead to adenocarcinoma.
Negative_regulation (regulation) of AKT protein
1) Confidence 0.06 Published 2004 Journal Clin. Cancer Res. Section Body Doc Link 15570007 Disease Relevance 0 Pain Relevance 0

General Comments

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