INT123542

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Context Info
Confidence 0.59
First Reported 2004
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 0.94
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Sepp1) growth (Sepp1) extracellular region (Sepp1)
Anatomy Link Frequency
spines 1
primary somatosensory cortex 1
Sepp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
primary somatosensory cortex 18 99.80 Very High Very High Very High
ketamine 1 99.04 Very High Very High Very High
Analgesic 3 77.88 Quite High
MU agonist 2 76.32 Quite High
long-term potentiation 12 68.32 Quite High
potassium channel 4 64.72 Quite High
analgesia 2 55.84 Quite High
Glutamate receptor 5 33.44 Quite Low
imagery 27 27.60 Quite Low
Pain 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 14 93.92 High High
Nociception 2 80.68 Quite High
Erectile Dysfunction 246 78.88 Quite High
Sleep Disorders 1 71.56 Quite High
Diabetes Mellitus 60 62.56 Quite High
Alzheimer's Dementia 5 50.00 Quite Low
Cv Unclassified Under Development 18 28.00 Quite Low
Dyslipidemia /

Combined Dyslipidemia

2 25.92 Quite Low
Disease 21 5.00 Very Low Very Low Very Low
Lower Urinary Tract Symptoms 16 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrated that when compared to the VPL-SEP and SI-SEP, the Vx-SEP was modulated differently by the experimental conditions.
Regulation (modulated) of Vx-SEP associated with primary somatosensory cortex
1) Confidence 0.59 Published 2005 Journal Brain Res. Bull. Section Abstract Doc Link 16182934 Disease Relevance 0 Pain Relevance 0.30
These results demonstrated that when compared to the VPL-SEP and SI-SEP, the Vx-SEP was modulated differently by the experimental conditions.
Regulation (modulated) of Vx-SEP associated with primary somatosensory cortex
2) Confidence 0.43 Published 2005 Journal Brain Res. Bull. Section Abstract Doc Link 16182934 Disease Relevance 0 Pain Relevance 0.30
While the SI-SEP and AI-AEP were minimally but significantly affected, fentanyl dose-dependently decreased the Vx-SEP and Vx-AEP.
Regulation (affected) of Vx-SEP
3) Confidence 0.25 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 16861104 Disease Relevance 0.26 Pain Relevance 0.07
The SI-SEP positive component (P) occurring at 12 ms after stimulation (P12) showed a significantly lower intensity threshold and was significantly less affected by increasing stimulus frequency and by administration of the different drugs when compared to the Vx-SEP P15.
Regulation (affected) of SI-SEP
4) Confidence 0.24 Published 2004 Journal Brain Res. Section Abstract Doc Link 15571674 Disease Relevance 0.08 Pain Relevance 0.26
While the SI-SEP and AI-AEP were minimally but significantly affected, fentanyl dose-dependently decreased the Vx-SEP and Vx-AEP.
Regulation (affected) of SI-SEP
5) Confidence 0.22 Published 2006 Journal Brain Res. Bull. Section Abstract Doc Link 16861104 Disease Relevance 0.26 Pain Relevance 0.07
The IIEF-EF and SEP data are summarized in Figure 3.
Regulation (summarized) of SEP
6) Confidence 0.21 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2643112 Disease Relevance 0.14 Pain Relevance 0
RESULTS: The primary somatosensory cortex-evoked potentials were not affected by the dexmedetomidine CRI, but the other three parameters were significantly affected; although the AI-SEP to a lesser extent than the Vx-SEP and Vx-AEP.
Regulation (affected) of AI-SEP in primary somatosensory cortex
7) Confidence 0.21 Published 2008 Journal Vet Anaesth Analg Section Body Doc Link 18466160 Disease Relevance 0.07 Pain Relevance 0
Efficacy was measured by changes in the IIEF-EF score, SEP, and the GAQ.
Regulation (changes) of SEP
8) Confidence 0.12 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2643112 Disease Relevance 0.13 Pain Relevance 0
monomers had no effect on SEP-GluR1 signals at dendritic spines (Figure 1c), confirming the notion that A?
Neg (no) Regulation (effect) of SEP-GluR1 in spines
9) Confidence 0.02 Published 2010 Journal Mol Brain Section Body Doc Link PMC2853530 Disease Relevance 0 Pain Relevance 0.09

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