INT123554

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Context Info
Confidence 0.72
First Reported 2004
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.13
Pain Relevance 1.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Dbi) transport (Dbi) mitochondrion (Dbi)
extracellular space (Dbi) plasma membrane (Dbi) nucleus (Dbi)
Dbi (Rattus norvegicus)
Pain Link Frequency Relevance Heat
addiction 9 99.72 Very High Very High Very High
opiate 4 99.50 Very High Very High Very High
Morphine 7 98.08 Very High Very High Very High
electroacupuncture 6 97.16 Very High Very High Very High
withdrawal 5 89.44 High High
Hippocampus 1 64.72 Quite High
Nucleus accumbens 1 60.80 Quite High
amygdala 1 58.56 Quite High
psychological dependence 1 43.36 Quite Low
Inflammation 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Opiate Addiction 2 99.72 Very High Very High Very High
Diabetes Mellitus 62 99.56 Very High Very High Very High
Anxiety Disorder 3 99.40 Very High Very High Very High
Morphine Dependence 6 98.00 Very High Very High Very High
Diabetic Retinopathy 17 44.88 Quite Low
Disease 1 12.08 Low Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Apoptosis 5 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The transcription of the DBI mRNA of the electroacupuncture group was obviously lower than that of the morphine group (P<0.05), and there was no difference between the electroacupuncture group and control group.
Transcription (transcription) of DBI mRNA
1) Confidence 0.72 Published 2004 Journal Sichuan Da Xue Xue Bao Yi Xue Ban Section Body Doc Link 15573765 Disease Relevance 0.15 Pain Relevance 0
CONCLUSION: Electroacupuncture can weaken the CPP of the morphine dependence rats, and the neurobiological mechanism may be related to the electroacupuncture-induced transcription of DBI mRNA.


Transcription (transcription) of DBI mRNA
2) Confidence 0.72 Published 2004 Journal Sichuan Da Xue Xue Bao Yi Xue Ban Section Body Doc Link 15573765 Disease Relevance 0.12 Pain Relevance 0
OBJECTIVE: To address the research questions whether electroacupuncture can weaken the CPP of morphine dependence rats and whether the neurobiological mechanism for control of anxiety is related to the transcription of DBI mRNA.
Transcription (transcription) of DBI mRNA associated with addiction, anxiety disorder, electroacupuncture and morphine
3) Confidence 0.72 Published 2004 Journal Sichuan Da Xue Xue Bao Yi Xue Ban Section Abstract Doc Link 15573765 Disease Relevance 0.27 Pain Relevance 0.35
Using conditioned place preference (CPP) rat model and in situ hybridization technique, we examined the correlation between opiate dependence and the mRNA expression of DBI.
Transcription (expression) of DBI associated with addiction and opiate
4) Confidence 0.63 Published 2005 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 15950760 Disease Relevance 0.19 Pain Relevance 0.78
The diabetes-induced increases in Dbi and Anxa5 protein and mRNA expression were completely normalized (Figure 8).
Transcription (expression) of Dbi associated with diabetes mellitus
5) Confidence 0.44 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020973 Disease Relevance 0.39 Pain Relevance 0

General Comments

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