INT123578

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Context Info
Confidence 0.33
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Snai1) cytoplasm (Snai1)
Anatomy Link Frequency
heart 2
Snai1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 4 97.36 Very High Very High Very High
Opioid 1 83.92 Quite High
antagonist 1 83.36 Quite High
narcan 1 82.48 Quite High
opioid receptor 1 82.12 Quite High
Raphe 1 67.76 Quite High
Rostral ventrolateral medulla 3 46.96 Quite Low
mu opioid receptor 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Obesity 12 99.14 Very High Very High Very High
Fever 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increases in brown adipose tissue (BAT) sympathetic nerve activity (SNA) (peak, +326% of control), BAT temperature (peak, +0.8 degrees C), renal SNA (peak, +146% of control), and heart rate (HR; peak, +32 beats/min) produced by intravenous fentanyl were abolished by premamillary transection of the neuraxis but were mimicked by intracerebroventricular administration of fentanyl, which also increased arterial pressure (AP; peak, +12 mmHg).
Negative_regulation (abolished) of Gene_expression (produced) of SNA in heart associated with obesity and intracerebroventricular
1) Confidence 0.33 Published 2005 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 15576661 Disease Relevance 0.50 Pain Relevance 0.36

General Comments

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