INT123589

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Context Info
Confidence 0.50
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 2.92
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (Vgf) extracellular space (Vgf) extracellular region (Vgf)
Anatomy Link Frequency
nucleus 12
Vgf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropathic pain 11 94.48 High High
Dorsal horn neuron 13 85.40 High High
Spinal cord 9 83.84 Quite High
Peripheral nerve injury 7 74.76 Quite High
depression 1 71.00 Quite High
Hippocampus 3 69.96 Quite High
Morphine 6 62.64 Quite High
Neuropeptide 8 50.00 Quite Low
Peripheral nervous system 1 48.00 Quite Low
Inflammation 1 31.36 Quite Low
Disease Link Frequency Relevance Heat
Nervous System Injury 31 99.98 Very High Very High Very High
Erectile Dysfunction 42 99.44 Very High Very High Very High
Neuropathic Pain 17 94.48 High High
Injury 11 78.40 Quite High
Depression 1 71.00 Quite High
INFLAMMATION 1 31.36 Quite Low
Nociception 2 25.76 Quite Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of five peptides derived from the C-terminal portion of rat pro-VGF (VGF(577-617), VGF(588-617), VGF(599-617), VGF(556-576) and VGF(588-597)) on penile erection was studied after injection into the hypothalamic paraventricular nucleus of male rats.
Positive_regulation (derived) of Positive_regulation (portion) of VGF in nucleus associated with erectile dysfunction
1) Confidence 0.50 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15579158 Disease Relevance 0.32 Pain Relevance 0.06
The effect of five peptides derived from the C-terminal portion of rat pro-VGF (VGF(577-617), VGF(588-617), VGF(599-617), VGF(556-576) and VGF(588-597)) on penile erection was studied after injection into the hypothalamic paraventricular nucleus of male rats.
Positive_regulation (derived) of Positive_regulation (portion) of VGF in nucleus associated with erectile dysfunction
2) Confidence 0.50 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15579158 Disease Relevance 0.32 Pain Relevance 0.06
The effect of five peptides derived from the C-terminal portion of rat pro-VGF (VGF(577-617), VGF(588-617), VGF(599-617), VGF(556-576) and VGF(588-597)) on penile erection was studied after injection into the hypothalamic paraventricular nucleus of male rats.
Positive_regulation (derived) of Positive_regulation (portion) of VGF in nucleus associated with erectile dysfunction
3) Confidence 0.50 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15579158 Disease Relevance 0.31 Pain Relevance 0.06
Figure 1A shows that SNI triggers a sustained 3 fold upregulation of VGF mRNA that is maintained for at least 3 weeks.
Positive_regulation (triggers) of Positive_regulation (upregulation) of VGF associated with nervous system injury
4) Confidence 0.47 Published 2008 Journal Mol Pain Section Body Doc Link PMC2614976 Disease Relevance 1.00 Pain Relevance 0.52
The effect of five peptides derived from the C-terminal portion of rat pro-VGF (VGF(577-617), VGF(588-617), VGF(599-617), VGF(556-576) and VGF(588-597)) on penile erection was studied after injection into the hypothalamic paraventricular nucleus of male rats.
Positive_regulation (derived) of Positive_regulation (portion) of VGF in nucleus associated with erectile dysfunction
5) Confidence 0.44 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15579158 Disease Relevance 0.32 Pain Relevance 0.06
The effect of five peptides derived from the C-terminal portion of rat pro-VGF (VGF(577-617), VGF(588-617), VGF(599-617), VGF(556-576) and VGF(588-597)) on penile erection was studied after injection into the hypothalamic paraventricular nucleus of male rats.
Positive_regulation (derived) of Positive_regulation (portion) of VGF in nucleus associated with erectile dysfunction
6) Confidence 0.44 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15579158 Disease Relevance 0.33 Pain Relevance 0.06
The effect of five peptides derived from the C-terminal portion of rat pro-VGF (VGF(577-617), VGF(588-617), VGF(599-617), VGF(556-576) and VGF(588-597)) on penile erection was studied after injection into the hypothalamic paraventricular nucleus of male rats.
Positive_regulation (derived) of Positive_regulation (portion) of VGF in nucleus associated with erectile dysfunction
7) Confidence 0.44 Published 2004 Journal Eur. J. Neurosci. Section Abstract Doc Link 15579158 Disease Relevance 0.32 Pain Relevance 0.06

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