INT123664

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (F2R) Golgi apparatus (F2R) plasma membrane (F2R)
signal transducer activity (F2R)
Anatomy Link Frequency
platelets 1
F2R (Homo sapiens)
PAR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 89.64 High High
Inflammation 1 78.48 Quite High
agonist 1 61.20 Quite High
aspirin 6 58.08 Quite High
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 1 89.64 High High
Acute Coronary Syndrome 3 88.44 High High
Atherosclerotic Plaque 1 82.04 Quite High
INFLAMMATION 1 78.48 Quite High
Hemorrhage 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment of platelets with thrombin (activates PAR1 and PAR4 thrombin receptors), SFLLRN (PAR1), AYPGKF (PAR4), collagen (alpha2beta1 and GPVI/FCgammaIIR receptors) and U46619 (TXA(2)) resulted in strong activation of p38 MAPK.
thrombin Positive_regulation (activates) of PAR4 in platelets
1) Confidence 0.03 Published 2004 Journal Thromb. Haemost. Section Abstract Doc Link 15583748 Disease Relevance 0.51 Pain Relevance 0.19

General Comments

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