INT123783

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Context Info
Confidence 0.08
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.68
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Bid) mitochondrion (Bid) cytoplasm (Bid)
Anatomy Link Frequency
hippocampus 1
Bid (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 6 99.54 Very High Very High Very High
anesthesia 2 86.88 High High
isoflurane 1 84.68 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 3 100.00 Very High Very High Very High
Neurodegenerative Disease 4 80.32 Quite High
Stress 1 75.00 Quite High
Hypertension 1 67.28 Quite High
Increased Venous Pressure Under Development 1 65.68 Quite High
Hypoxia 1 63.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compared with vehicle, ANG II increased mean arterial pressure (107 +/- 4 vs. 146 +/- 6 mmHg; P < 0.001), renal vascular resistance (42 +/- 3 vs. 65 +/- 7 mmHg.ml(-1).min(-1).100 g(-1); P < 0.001), renal cortical NADPH oxidase activity (2.3 +/- 0.2 vs. 3.6 +/- 0.4 nmol O(2)(-)..min(-1).mg(-1) protein; P < 0.05), mRNA and protein expression for p22(phox) (2.1- and 1.8-fold respectively; P < 0.05) and reduced the mRNA for extracellular (EC)-SOD (-1.8 fold; P < 0.05).
Transcription (activity) of p22
1) Confidence 0.08 Published 2005 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 15598867 Disease Relevance 0.27 Pain Relevance 0.09
At 1 h after CPB, in 6 rats per group, hippocampus was processed for the apoptotic gene (bcl-2 and bax) messenger RNAs detection by reverse transcriptase polymerase chain reaction, and messenger RNA expression was determined by the ratio of the polymerase chain reaction product of bcl-2 or bax to the beta-actin gene.
Transcription (detection) of apoptotic gene in hippocampus associated with hippocampus and apoptosis
2) Confidence 0.01 Published 2006 Journal Anesth. Analg. Section Abstract Doc Link 16551891 Disease Relevance 0.41 Pain Relevance 0.25

General Comments

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