INT123793

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Kcnq2) transmembrane transport (Kcnq2)
Kcnq2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Analgesic 1 89.76 High High
diclofenac 5 85.84 High High
cINOD 1 81.08 Quite High
potassium channel 2 79.00 Quite High
Neuronal excitability 2 78.08 Quite High
anticonvulsant 2 75.00 Quite High
Action potential 1 70.88 Quite High
hyperexcitability 1 55.36 Quite High
Pain 3 55.04 Quite High
Migraine 1 52.32 Quite High
Disease Link Frequency Relevance Heat
Epilepsy 3 86.00 High High
INFLAMMATION 1 80.84 Quite High
Benign Neonatal Epilepsy 1 70.08 Quite High
Pain 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Convulsion 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of the drugs were stronger on KCNQ2 than on KCNQ3 channel alpha subunits.
Regulation (stronger) of KCNQ2
1) Confidence 0.44 Published 2005 Journal Mol. Pharmacol. Section Abstract Doc Link 15598972 Disease Relevance 0.22 Pain Relevance 0.55
Here we identify two mechanisms responsible for regulating KCNQ2 and KCNQ3 mRNA levels.
Regulation (regulating) of KCNQ2
2) Confidence 0.17 Published 2010 Journal J. Neurosci. Section Abstract Doc Link 20926649 Disease Relevance 0.09 Pain Relevance 0.26

General Comments

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