INT123794

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Context Info
Confidence 0.46
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.26
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Kcnq2) transmembrane transport (Kcnq2)
Anatomy Link Frequency
ovary 2
Kcnq2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
diclofenac 5 99.54 Very High Very High Very High
cINOD 1 94.32 High High
anticonvulsant 2 75.00 Quite High
potassium channel 1 75.00 Quite High
Action potential 1 45.84 Quite Low
hyperexcitability 1 30.32 Quite Low
Migraine 1 27.28 Quite Low
Neuropathic pain 1 26.24 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 1 94.08 High High
Epilepsy 2 84.48 Quite High
Benign Neonatal Epilepsy 1 83.32 Quite High
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Extracellular application of meclofenamate (EC(50) = 25 microM) and diclofenac (EC(50) = 2.6 microM) resulted in the activation of KCNQ2/Q3 K(+) currents, heterologously expressed in Chinese hamster ovary cells.
Positive_regulation (resulted) of Positive_regulation (activation) of KCNQ2 in ovary associated with diclofenac
1) Confidence 0.46 Published 2005 Journal Mol. Pharmacol. Section Abstract Doc Link 15598972 Disease Relevance 0.26 Pain Relevance 0.33

General Comments

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