INT123831

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2007
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ucn)
Ucn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
tetrodotoxin 3 96.28 Very High Very High Very High
antagonist 2 94.72 High High
noradrenaline 1 84.68 Quite High
Central nervous system 1 75.84 Quite High
anesthesia 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of UcnI on both types of contraction were also studied in the presence of antalarmin, astressin2-B, tetrodotoxin (TTX), atropine, and 5-HT antagonists.
Regulation (effects) of UcnI associated with tetrodotoxin and antagonist
1) Confidence 0.42 Published 2007 Journal Am. J. Physiol. Gastrointest. Liver Physiol. Section Abstract Doc Link 17717045 Disease Relevance 0 Pain Relevance 0.38
In addition, methylene blue (inhibitor of soluble guanylyl cyclase, i.v. infusion), indomethacin (cyclooxygenase inhibitor, i.v. bolus), glibenclamide (blocker of ATP-sensitive K(+)-channels, i.v. bolus) or tetraethylammonium (a non specific K(+)-channel blocker, i.v. bolus) did not affect the depressor effect of urocortin.
Neg (not) Regulation (affect) of urocortin
2) Confidence 0.19 Published 2005 Journal Pharmacology Section Abstract Doc Link 15604589 Disease Relevance 0 Pain Relevance 0.04

General Comments

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