INT123841

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Context Info
Confidence 0.30
First Reported 2005
Last Reported 2010
Negated 3
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 1.93
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (MMD)
Anatomy Link Frequency
MMA 3
MCA 2
MMD (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 2 91.40 High High
Migraine 7 88.24 High High
Sumatriptan 4 50.00 Quite Low
headache 10 10.00 Low Low
Calcitonin gene-related peptide 10 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 5 100.00 Very High Very High Very High
Pressure Volume 2 Under Development 10 99.54 Very High Very High Very High
Headache 15 93.92 High High
Hypotension 2 92.64 High High
Cv General 3 Under Development 2 91.40 High High
Hypercapnia 2 89.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We recorded circumference changes of the middle meningeal artery (MMA) and middle cerebral artery (MCA) using magnetic resonance angiography before and after infusion (20 minutes) of 1.5 ?
Regulation (changes) of MMA in MCA
1) Confidence 0.30 Published 2010 Journal Neurology Section Body Doc Link 20975053 Disease Relevance 0.19 Pain Relevance 0
Explorative analysis revealed that sumatriptan had a more selective action on MMA compared with MCA on the CGRP day (p < 0.0001) and on the placebo day (p = 0.007).
Regulation (action) of MMA in MCA
2) Confidence 0.30 Published 2010 Journal Neurology Section Body Doc Link 20975053 Disease Relevance 0.14 Pain Relevance 0
The decrease in blood pressure did not significantly change the MMA (P=0.38); however, the PA diameter and the LCBF(Flux) were affected (P<0.001).
Neg (not) Regulation (change) of MMA in MMA associated with pressure volume 2 under development
3) Confidence 0.23 Published 2005 Journal Cephalalgia Section Abstract Doc Link 15606566 Disease Relevance 0.72 Pain Relevance 0.11
In contrast, the MMA does not autoregulate and MMA diameter changes in pharmacological studies may exclusively be due to direct pharmacological effects.
Neg (not) Regulation (autoregulate) of MMA in MMA
4) Confidence 0.23 Published 2005 Journal Cephalalgia Section Abstract Doc Link 15606566 Disease Relevance 0.61 Pain Relevance 0.03
There were no dramatic changes of vasodilation in the MMA during the attack (2.0 mm), attack-free period (diameter 1.9 mm), or period after medication (1.7 mm), resembling extrapolations of observations in experimental animal models.
Neg (no) Regulation (changes) of MMA in MMA associated with increased venous pressure under development
5) Confidence 0.08 Published 2009 Journal Intern. Med. Section Abstract Doc Link 20009407 Disease Relevance 0.26 Pain Relevance 0.24

General Comments

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