INT12413

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Context Info
Confidence 0.76
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 14
Disease Relevance 3.13
Pain Relevance 1.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MPG) nucleus (MPG) DNA binding (MPG)
Anatomy Link Frequency
endothelium 1
MPG (Homo sapiens)
Pain Link Frequency Relevance Heat
rapifen 9 99.00 Very High Very High Very High
Analgesic 1 96.16 Very High Very High Very High
adenocard 248 95.92 Very High Very High Very High
rheumatoid arthritis 2 95.88 Very High Very High Very High
antagonist 20 94.40 High High
b2 receptor 12 93.36 High High
bradykinin 164 84.24 Quite High
palliative 2 84.20 Quite High
imagery 2 78.52 Quite High
headache 1 72.52 Quite High
Disease Link Frequency Relevance Heat
Thalassemia 4 97.28 Very High Very High Very High
Renal Failure 2 96.92 Very High Very High Very High
Sickle Cell Anemia 4 96.60 Very High Very High Very High
Brain Tumor 2 96.44 Very High Very High Very High
Cirrhosis 2 96.32 Very High Very High Very High
Rheumatoid Arthritis 2 95.88 Very High Very High Very High
Increased Venous Pressure Under Development 4 95.12 Very High Very High Very High
Myocardial Infarction 7 94.88 High High
Cancer 12 91.64 High High
Congenital Anomalies 1 88.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Real time reverse transcriptase polymerase chain reaction (RT-PCR) assessed MPG expression and three reference genes namely; beta Actin (ACTB), Glyceraldehyde three phosphate dehydrogenase (GAPDH) and Ubiquitin c (UBC).
Gene_expression (expression) of MPG
1) Confidence 0.76 Published 2009 Journal J. Photochem. Photobiol. B, Biol. Section Body Doc Link 19101162 Disease Relevance 0 Pain Relevance 0
Real time RT-PCR showed that ACTB was not influenced by cell culture conditions or laser irradiation, and MPG expression was not detected.
Gene_expression (expression) of MPG
2) Confidence 0.76 Published 2009 Journal J. Photochem. Photobiol. B, Biol. Section Body Doc Link 19101162 Disease Relevance 0 Pain Relevance 0
Wounded cells were irradiated once (30 min) with 16 J/cm(2), and MPG expression was assessed at 0, 3 and 8h post-laser irradiation.
Gene_expression (expression) of MPG
3) Confidence 0.76 Published 2009 Journal J. Photochem. Photobiol. B, Biol. Section Body Doc Link 19101162 Disease Relevance 0 Pain Relevance 0
Binding of alfentanil was measured in human alpha 1-acid glycoprotein (AAG) and human albumin solutions, and in serum from 6 groups of individuals: control subjects, patients with renal failure, cirrhosis, rheumatoid arthritis and myocardial infarction, and intensive care patients.
Gene_expression (solutions) of AAG associated with rapifen, cirrhosis, renal failure, rheumatoid arthritis and myocardial infarction
4) Confidence 0.65 Published 1991 Journal Int J Clin Pharmacol Ther Toxicol Section Abstract Doc Link 2071261 Disease Relevance 0.70 Pain Relevance 0.39
Superoxide dismutase, GSH, MPG and NAC also produced endothelium-dependent relaxations similar to captopril.
Gene_expression (produced) of MPG in endothelium
5) Confidence 0.35 Published 1991 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 1646324 Disease Relevance 0.24 Pain Relevance 0.07
An increasing number of DNA repair proteins have been shown to have cell-cycle-dependent expression, including UNG2, RAD51, RAD52, APE, hNTH1, ANPG and hMYH (48,61–65).
Gene_expression (expression) of ANPG
6) Confidence 0.29 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1072800 Disease Relevance 0 Pain Relevance 0.03
The effect of MPG, SPT, and HOE140 alone was studied in separate groups exposed to 150 ?
Gene_expression (alone) of MPG
7) Confidence 0.18 Published 2010 Journal BMC Anesthesiol Section Body Doc Link PMC2919536 Disease Relevance 0.06 Pain Relevance 0.38
M N-mercaptopropionylglycine, a ROS scavenger (Des + MPG; n = 6), 100 ?
Gene_expression (scavenger) of MPG
8) Confidence 0.18 Published 2010 Journal BMC Anesthesiol Section Body Doc Link PMC2919536 Disease Relevance 0.13 Pain Relevance 0.24
M N-mercaptopropionylglycine (MPG; n = 6), 100 ?
Gene_expression (mercaptopropionylglycine) of MPG
9) Confidence 0.18 Published 2010 Journal BMC Anesthesiol Section Body Doc Link PMC2919536 Disease Relevance 0.05 Pain Relevance 0.43
Desflurane-induced enhanced recovery of FoC at the end of reoxygenation was abolished (P < 0.0001) in presence of MPG (FoC60: 54 ± 3% of baseline), SPT (FoC60: 62 ± 9% of baseline), HOE 140 (FoC60: 58 ± 6% of baseline).
Gene_expression (presence) of MPG
10) Confidence 0.18 Published 2010 Journal BMC Anesthesiol Section Body Doc Link PMC2919536 Disease Relevance 0.21 Pain Relevance 0.13
In the past 4 years, significant advances have been made toward this goal using lentiviral vectors to obtain high-level expression of complex globin gene cassettes.
Gene_expression (expression) of globin gene
11) Confidence 0.10 Published 2004 Journal Semin. Hematol. Section Abstract Doc Link 15508113 Disease Relevance 0.58 Pain Relevance 0.08
Analysis revealed no mutations of the VHL gene in 5 regions, exon 5-8 of the p53 gene, exon 1-2 of the p16 gene and exon 5,6 and 8 of the PTEN gene.
Gene_expression (exon) of p16 gene
12) Confidence 0.03 Published 2005 Journal Med. J. Malaysia Section Abstract Doc Link 16379193 Disease Relevance 0.58 Pain Relevance 0.11
Using lentiviral vectors to obtain high-level expression of complex globin gene cassettes, therapeutic correction of several murine models of beta-thalassemia, and sickle cell disease was recently reported.
Gene_expression (expression) of globin gene associated with sickle cell anemia and thalassemia
13) Confidence 0.03 Published 2003 Journal Curr. Hematol. Rep. Section Abstract Doc Link 12901333 Disease Relevance 0.59 Pain Relevance 0.08
CRD4–7 binding to sE was investigated by blot overlay by running 0.9ug sE protein and 0.9ug sE protein deglycosylated with peptide: N-glycosidase F (New England Biolabs) on 10% SDS-PAGE, and subsequently transferring proteins to Hybond C-Extra nitrocellulose membranes (Pharmacia).
Gene_expression (transferring) of N-glycosidase F
14) Confidence 0.01 Published 2008 Journal PLoS Pathogens Section Body Doc Link PMC2233670 Disease Relevance 0 Pain Relevance 0

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