INT124352

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Context Info
Confidence 0.10
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
Golgi apparatus (Gorasp2)
Il6 (Rattus norvegicus)
Gorasp2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
intrathecal 4 95.24 Very High Very High Very High
antagonist 3 88.84 High High
Dorsal horn 1 81.84 Quite High
Spinal cord 1 81.36 Quite High
Peripheral nerve injury 3 75.00 Quite High
nMDA receptor 2 75.00 Quite High
Neuropathic pain 3 66.20 Quite High
agonist 1 61.68 Quite High
dexamethasone 1 61.04 Quite High
Pain 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Nervous System Injury 11 99.72 Very High Very High Very High
Targeted Disruption 1 99.44 Very High Very High Very High
Nociception 1 84.88 Quite High
Neuropathic Pain 3 66.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because IL-6 and PKCgamma mediated the upregulation of central GRs after CCI as demonstrated previously, the results suggest that IL-6 and PKCgamma served as cellular mediators contributing to the GR-mediated expression of NMDARs after CCI.
IL-6 Positive_regulation (mediated) of Positive_regulation (upregulation) of GRs associated with nervous system injury
1) Confidence 0.10 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 15647493 Disease Relevance 1.19 Pain Relevance 0.73

General Comments

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