INT124379

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Prodh2) Golgi apparatus (App) extracellular matrix organization (App)
DNA binding (App) cytoplasm (App) oxidoreductase activity (Prodh2)
Anatomy Link Frequency
cleavage 2
Prodh2 (Mus musculus)
App (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Abeta 3 97.88 Very High Very High Very High
cINOD 1 81.80 Quite High
Inflammation 2 81.32 Quite High
Neurotransmitter 1 74.24 Quite High
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 3 100.00 Very High Very High Very High
Toxicity 1 98.24 Very High Very High Very High
Drug Induced Neurotoxicity 2 86.64 High High
INFLAMMATION 2 81.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, IBU-PO enhances, dose-dependently, the non-amyloidogenic amyloid precursor protein (APP) cleavage by increasing secreted APP and decreasing endogenous Abeta1-40 in rat hippocampal neurons.
IBU-PO Positive_regulation (increasing) of Localization (secreted) of APP in cleavage associated with alzheimer's dementia
1) Confidence 0.00 Published 2005 Journal Neurobiol. Dis. Section Abstract Doc Link 15649708 Disease Relevance 0.66 Pain Relevance 0.33

General Comments

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