INT124384

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Context Info
Confidence 0.40
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ADRBK1, MC1R) pigmentation (MC1R) cytosol (ADRBK1)
signal transduction (ADRBK1) aging (ADRBK1) signal transducer activity (MC1R)
ADRBK1 (Homo sapiens)
MC1R (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 6 100.00 Very High Very High Very High
agonist 5 99.96 Very High Very High Very High
Kinase C 1 84.76 Quite High
Disease Link Frequency Relevance Heat
Skin Cancer 5 92.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, GRK6, but not GRK2, was able to inhibit MC1R agonist-independent constitutive signaling.
GRK2 Negative_regulation (inhibit) of MC1R associated with melanocortin 1 receptor and agonist
1) Confidence 0.40 Published 2005 Journal Mol. Endocrinol. Section Abstract Doc Link 15650023 Disease Relevance 0.42 Pain Relevance 0.77

General Comments

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