INT124388

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.41
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GRK6)
GRK6 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 5 97.28 Very High Very High Very High
melanocortin 1 receptor 6 96.04 Very High Very High Very High
Kinase C 1 92.08 High High
Disease Link Frequency Relevance Heat
Skin Cancer 5 95.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cotransfection of the receptor and GRK2 or GRK6 genes in heterologous cells demonstrated that GRK2 and GRK6 impair agonist-dependent signaling by MC1R or Mc1r.
Positive_regulation (Cotransfection) of Gene_expression (Cotransfection) of GRK6 associated with melanocortin 1 receptor and agonist
1) Confidence 0.45 Published 2005 Journal Mol. Endocrinol. Section Abstract Doc Link 15650023 Disease Relevance 0.41 Pain Relevance 0.75

General Comments

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