INT124571

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Context Info
Confidence 0.07
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.07
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HPD) small molecule metabolic process (HPD) Golgi apparatus (HPD)
endoplasmic reticulum (HPD) cellular nitrogen compound metabolic process (HPD)
Anatomy Link Frequency
hypothalamus 1
preoptic area 1
HPD (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 18 100.00 Very High Very High Very High
Endogenous opioid 2 65.20 Quite High
Inflammation 12 57.60 Quite High
cytokine 29 56.56 Quite High
agonist 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 70 91.96 High High
Infection 55 77.88 Quite High
Stress 2 71.52 Quite High
INFLAMMATION 13 57.60 Quite High
Latent Tuberculosis 6 50.00 Quite Low
Lymphatic Filariasis 7 5.00 Very Low Very Low Very Low
Worm Infection 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Autoimmune Disease 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neurons that expressed PPD mRNA and DYN A immunoreactivity were widely distributed in the ovine preoptic area and hypothalamus.
Regulation (immunoreactivity) of PPD in hypothalamus associated with dynorphin
1) Confidence 0.07 Published 2005 Journal Neuroscience Section Abstract Doc Link 15664697 Disease Relevance 0.07 Pain Relevance 0.41
Neurons that expressed PPD mRNA and DYN A immunoreactivity were widely distributed in the ovine preoptic area and hypothalamus.
Regulation (immunoreactivity) of PPD in preoptic area associated with dynorphin
2) Confidence 0.03 Published 2005 Journal Neuroscience Section Abstract Doc Link 15664697 Disease Relevance 0.07 Pain Relevance 0.41
0.0340]; GM fold change of 0.9469 in PPD+Fil+ vs. 2.513 in PPD+Fil?
Regulation (change) of PPD
3) Confidence 0.02 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2710006 Disease Relevance 0.93 Pain Relevance 0.06

General Comments

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