INT124572

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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.95
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HPD) small molecule metabolic process (HPD) Golgi apparatus (HPD)
endoplasmic reticulum (HPD) cellular nitrogen compound metabolic process (HPD)
HPD (Homo sapiens)
Pain Link Frequency Relevance Heat
Dynorphin 9 99.08 Very High Very High Very High
Endogenous opioid 1 82.88 Quite High
Inflammation 24 59.36 Quite High
cytokine 58 58.32 Quite High
agonist 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 140 91.96 High High
Stress 1 89.20 High High
Infection 110 77.88 Quite High
INFLAMMATION 26 59.36 Quite High
Latent Tuberculosis 12 50.00 Quite Low
Lymphatic Filariasis 14 5.00 Very Low Very Low Very Low
Worm Infection 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Autoimmune Disease 4 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although DYN is involved in a number of hypothalamic functions in the sheep, little is known regarding the localization of preprodynorphin (PPD) expression and its major product DYN A (1-17).
Regulation (localization) of Gene_expression (expression) of PPD associated with dynorphin
1) Confidence 0.12 Published 2005 Journal Neuroscience Section Abstract Doc Link 15664697 Disease Relevance 0.09 Pain Relevance 0.39
0.0340]; GM fold change of 0.9469 in PPD+Fil+ vs. 2.513 in PPD+Fil?
Regulation (change) of Gene_expression (2.513) of PPD
2) Confidence 0.02 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2710006 Disease Relevance 0.93 Pain Relevance 0.06
0.0340]; GM fold change of 0.9469 in PPD+Fil+ vs. 2.513 in PPD+Fil?
Regulation (change) of Gene_expression (2.513) of PPD
3) Confidence 0.02 Published 2009 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2710006 Disease Relevance 0.93 Pain Relevance 0.06

General Comments

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