INT124603

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Context Info
Confidence 0.16
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.17
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

RNA binding (Ifih1) nucleus (Ifih1) intracellular (Ifih1)
helicase activity (Ifih1) DNA binding (Ifih1) cytoplasm (Ifih1)
Anatomy Link Frequency
gastrocnemius 2
Ifih1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 11 98.40 Very High Very High Very High
Osteoarthritis 3 89.04 High High
Pain score 1 86.80 High High
Pain 2 71.92 Quite High
COX-2 inhibitor 1 71.20 Quite High
cINOD 2 66.04 Quite High
Inflammation 23 50.00 Quite Low
Analgesic 1 37.64 Quite Low
cOX1 1 25.00 Low Low
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 2 100.00 Very High Very High Very High
Osteoarthritis 1 89.04 High High
Pain 3 86.80 High High
Aging 4 85.12 High High
Eating Disorder 2 82.40 Quite High
Knee Osteoarthritis 2 81.68 Quite High
Stress 55 78.48 Quite High
INFLAMMATION 24 65.48 Quite High
Toxicity 1 54.36 Quite High
Apoptosis 34 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Tenoxicam-treated patients had significant decrease in nitrite levels (p = 0.036) and XO activity (p = 0.01), but their SOD, GSH-Px enzyme activities, and MDA levels were unchanged from baseline.
Neg (unchanged) Positive_regulation (unchanged) of Gene_expression (levels) of MDA
1) Confidence 0.16 Published 2005 Journal Ann. Clin. Lab. Sci. Section Abstract Doc Link 15943176 Disease Relevance 0.61 Pain Relevance 0.52
Acetaminophen treatment caused a significant (P < 0.05-0.001) decrease in GSH levels whereas MDA levels and MPO activity were increased in both tissues.
Positive_regulation (increased) of Gene_expression (levels) of MDA associated with paracetamol and urological neuroanatomy
2) Confidence 0.06 Published 2005 Journal J Appl Toxicol Section Abstract Doc Link 15669031 Disease Relevance 0.23 Pain Relevance 0.71
We ascertained that females had significantly higher levels of MDA in the red gastrocnemius (32%, P?
Positive_regulation (levels) of Gene_expression (had) of MDA in gastrocnemius
3) Confidence 0.02 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827549 Disease Relevance 0.33 Pain Relevance 0

General Comments

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