INT124844

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.55
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Bcl2) aging (Bcl2) cell morphogenesis (Bcl2)
endoplasmic reticulum (Bcl2) intracellular (Bcl2) response to stress (Bcl2)
Bcl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 10 99.50 Very High Very High Very High
antagonist 1 98.64 Very High Very High Very High
Enkephalin 1 93.32 High High
Kinase C 1 82.80 Quite High
ischemia 27 81.84 Quite High
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
potassium channel 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 36 98.92 Very High Very High Very High
Hypoxia 8 98.64 Very High Very High Very High
Diabetes Mellitus 64 95.56 Very High Very High Very High
Apoptosis 50 95.04 Very High Very High Very High
Necrosis 13 94.88 High High
Stress 15 92.24 High High
Injury 23 87.60 High High
Cv Unclassified Under Development 27 81.84 Quite High
Stroke 2 78.60 Quite High
Death 4 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effects of L-arginine in expression of Bcl-2 mRNA and protein
Regulation (Effects) of Positive_regulation (arginine) of Bcl-2
1) Confidence 0.43 Published 2009 Journal Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association Section Body Doc Link PMC2841413 Disease Relevance 0.79 Pain Relevance 0.14
Effect of HO-1 induction on Bcl-2 in SHR and WKY rats
Regulation (Effect) of Positive_regulation (induction) of Bcl-2
2) Confidence 0.12 Published 2008 Journal International Journal of Molecular Sciences Section Body Doc Link PMC2635644 Disease Relevance 0.86 Pain Relevance 0
The DOR-mediated HPC protection depended on an increase in ERK and Bcl 2 activity, which counteracted the SH-induced increase in p38 MAPK activities and cytochrome c release.
Regulation (depended) of Positive_regulation (increase) of Bcl 2 associated with hypoxia and opioid receptor
3) Confidence 0.02 Published 2005 Journal J. Biol. Chem. Section Abstract Doc Link 15687501 Disease Relevance 0.90 Pain Relevance 0.61

General Comments

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